Metabolic Disorders in Polycystic Ovarian Syndrome
Recruitment status was Recruiting
The purpose of this study is to elucidate the significance of adipocytokine in women with PCOS among adiposity, hyperandrogenism and insulin resistance.
Polycystic Ovary Syndrome
|Study Design:||Observational Model: Defined Population
Observational Model: Natural History
Time Perspective: Cross-Sectional
Time Perspective: Prospective
|Study Start Date:||October 2004|
|Estimated Study Completion Date:||August 2005|
Polycystic ovary syndrome (PCOS) is the most common endocrinopathy in women of reproductive age with a probable prevalence of 5% to 10%. PCOS is characterized by chronic anovulation, menstrual irregularities, evidence of hyperandrogenism (either clinical, manifested as hirsutism, acne, male pattern balding, or biochemical, manifested by elevated serum adrenal and/or ovarian androgen concentration). Fifty percent of all patients with PCOS are obese, and the presence of obesity affects the clinical manifestations of PCOS. The underlying pathogenic mechanisms appear to involve insulin resistance and hyperinsulinemia, the magnitude of which is greater in obese than in non-obese women with PCOS.
|Contact: Mei-Jou Chen, M.D.||886-2-23123456 ext firstname.lastname@example.org|
|Department of Obstetrics and Gynecology, National Taiwan University Hospital||Recruiting|
|Contact: Mei-Jou Chen, M.D. 886-2-23123456 ext 3950 email@example.com|
|Study Director:||Horng-Nerng Ho, M.D.||NTUH|