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Understanding the Physiological Implications of Scanning Kelvin Probe Measurements

This study has suspended participant recruitment.
(Repair of minor software glitches)
Sponsor:
Information provided by (Responsible Party):
Andrew A. Ahn, Massachusetts General Hospital
ClinicalTrials.gov Identifier:
NCT01545973
First received: March 2, 2012
Last updated: NA
Last verified: March 2012
History: No changes posted

March 2, 2012
March 2, 2012
August 2011
August 2012   (final data collection date for primary outcome measure)
Surface Electrical Potential [ Time Frame: 1 day ] [ Designated as safety issue: No ]
The electrical potential of skin obtained from the Scanning Kelvin Probe
Same as current
No Changes Posted
Electrical Impedance [ Time Frame: One day ] [ Designated as safety issue: No ]
Electrical impedance (measurement) obtained through another, more conventional measurement device.
Same as current
Not Provided
Not Provided
 
Understanding the Physiological Implications of Scanning Kelvin Probe Measurements
Measuring Skin Electrical Potential With the Kelvin Probe: Underlying Physiology

The purpose of this study is to evaluate the effects of skin thickness, skin moisture, and sweat gland density on Scanning Kelvin Probe measurements.

The Scanning Kelvin Probe measures the electrical potential of material surfaces without actually touching it. Although this technology has been applied to non-living materials (e.g. metal and semiconductors) before, it has not been effectively applied to biological materials, much less to live human skin . This project aims to evaluate the use of Scanning Kelvin Probe to live human skin by investigating the effects of skin thickness, skin moisture, and sweat glands on Kelvin Probe measurements of electrical potential. Testing will be performed on the arms and hands of twenty four healthy individuals under different study conditions.
Observational
Observational Model: Case Control
Time Perspective: Cross-Sectional
Not Provided
Retention:   Samples With DNA
Description:

Whole Blood
Probability Sample

Healthy Volunteers
  • Healthy Individuals
  • Skin Electrical Potential
Other: Skin Moistening, Skin Denuding
Application of normal saline to skin and Tape stripping of the superficial skin
Healthy Volunteers
Human subjects without chronic medical conditions, defined as conditions requiring chronic medication use.
Intervention: Other: Skin Moistening, Skin Denuding
Not Provided

*   Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
 
Suspended
24
August 2012
August 2012   (final data collection date for primary outcome measure)

Inclusion Criteria:

  • "Healthy" is defined as not having a chronic medical condition requiring daily medications (hypertension, diabetes, hypothyroidism, etc)

Exclusion Criteria:

  • autonomic disorders (sweating irregularities), skin disorders, extensive burns/scars on the hand, tremors, neuromuscular conditions, restless leg syndrome, movement disorders, and implanted cardiac defibrillator/pacemaker
Both
18 Years to 65 Years
Yes
Contact information is only displayed when the study is recruiting subjects
United States
 
NCT01545973
55R21AT005249-02
No
Andrew A. Ahn, Massachusetts General Hospital
Massachusetts General Hospital
Not Provided
Principal Investigator: Andrew C. Ahn, MD, MPH Massachusetts General Hospital
Massachusetts General Hospital
March 2012

ICMJE     Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP