Presence of Minor Anti Phospholipid Antibodies in Blood Samples of Ischemic Stroke Patients and Healthy Controls

This study is not yet open for participant recruitment.
Verified December 2011 by Meir Medical Center
Sponsor:
Collaborator:
Sheba Medical Center
Information provided by (Responsible Party):
Meir Medical Center
ClinicalTrials.gov Identifier:
NCT01487746
First received: December 5, 2011
Last updated: December 6, 2011
Last verified: December 2011

December 5, 2011
December 6, 2011
December 2011
March 2012   (final data collection date for primary outcome measure)
Not Provided
Not Provided
Complete list of historical versions of study NCT01487746 on ClinicalTrials.gov Archive Site
Not Provided
Not Provided
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Presence of Minor Anti Phospholipid Antibodies in Blood Samples of Ischemic Stroke Patients and Healthy Controls
Presence of Minor Anti Phospholipid Antibodies in Blood Samples of Ischemic Stroke Patients and Healthy Controls.

The investigators expect to find higher levels of both classical and minor antiphospholipid (APL) antibodies among the stroke cases. Furthermore, the investigators expect to find not only classical APLA but also minor antibodies.

The investigators believe that minor antibodies have a major role in the hypercoagulability state.

Not Provided
Observational
Observational Model: Case Control
Time Perspective: Prospective
Not Provided
Retention:   Samples Without DNA
Description:

Serum samples of Stroke patients withdrawned within 36 hrs since stroke evoked. Healthy controls

Non-Probability Sample

on a bank of 207 stroke patients serum samples, and also on 40 healthy controls. The samples were collected during the acute phase of the ischemic event.

Ischemic Stroke
Not Provided
  • treatment
    Stroke patients
  • Controls
    healthy controls
Not Provided

*   Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
 
Not yet recruiting
207
September 2012
March 2012   (final data collection date for primary outcome measure)

Inclusion Criteria:

  • stroke diagnosis
  • blood sampling within 36hrs from the event
  • written agreement

Exclusion Criteria:

  • a stroke, MI or major operation prior to the current stroke
  • hypercoagulable state known in this patient
  • a severe chronic disease known at the time of the stroke
  • an infection on arrival (based on anamnesis, physical exam and lab tests)
  • thrombolytic treatment
Both
18 Years and older
Yes
Contact: Yair Levy, Prof. 0533671735 levy.yair@clalit.org.il,
Contact: Narin N Carmel, B.Sc 0547691482 carmeln@gmail.com
Israel
 
NCT01487746
0125-11-MMC
No
Meir Medical Center
Meir Medical Center
Sheba Medical Center
Not Provided
Meir Medical Center
December 2011

ICMJE     Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP