Efficacy and Safety of Titrated Oral Misoprostol Solution for Labor Induction at Term

The recruitment status of this study is unknown because the information has not been verified recently.
Verified March 2011 by University of Manitoba.
Recruitment status was  Recruiting
Sponsor:
Information provided by:
University of Manitoba
ClinicalTrials.gov Identifier:
NCT01070472
First received: February 16, 2010
Last updated: March 16, 2011
Last verified: March 2011

February 16, 2010
March 16, 2011
March 2010
November 2010   (final data collection date for primary outcome measure)
Rate of vaginal delivery within 24 hours [ Time Frame: 24 hours ] [ Designated as safety issue: No ]
Same as current
Complete list of historical versions of study NCT01070472 on ClinicalTrials.gov Archive Site
Uterine hyperstimulation rate [ Time Frame: 24 hours ] [ Designated as safety issue: Yes ]
Same as current
Not Provided
Not Provided
 
Efficacy and Safety of Titrated Oral Misoprostol Solution for Labor Induction at Term
Efficacy and Safety of Titrated Oral Misoprostol Solution for Labor Induction at Term

The purpose of this study is to determine whether a titrated solution of oral Misoprostol is safe and effective at inducing labor at term, regardless of Bishop Score.

Not Provided
Interventional
Not Provided
Allocation: Non-Randomized
Endpoint Classification: Safety/Efficacy Study
Intervention Model: Single Group Assignment
Masking: Open Label
Primary Purpose: Treatment
Labor Induction at Term
Drug: Misoprostol
titrated oral misoprostol solution
Not Provided
Not Provided

*   Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
 
Recruiting
250
December 2011
November 2010   (final data collection date for primary outcome measure)

Inclusion Criteria:

  1. term,
  2. singleton
  3. no contraindication to prostaglandins
  4. vertex
  5. no exposure to vaginal prostaglandins in the index pregnancy

Exclusion Criteria:

  1. parity > 3
  2. severe PIH: BP> 160/100, abnormal LFT's, proteinuria >1g/day
  3. previous uterine surgery
  4. regular uterine contractions
  5. maternal age > 45
  6. twins
Female
18 Years to 44 Years
No
Contact: debbie J Robinson, MD FRCSC 204 237 4634 drdrobinson@mts.net
Contact: Michael Helewa, MD FRCSC 204 237 2549 mhelewa@sbgh.mb.ca
Canada
 
NCT01070472
B2009:149
Yes
Dr. debbie Robinson, University of Manitoba
University of Manitoba
Not Provided
Principal Investigator: debbie J Robinson, MD FRCSC University of Manitoba
University of Manitoba
March 2011

ICMJE     Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP