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Genetics of Schizophrenia

The recruitment status of this study is unknown because the information has not been verified recently.
Verified February 2008 by Sheba Medical Center.
Recruitment status was  Not yet recruiting
Sponsor:
Information provided by:
Sheba Medical Center
ClinicalTrials.gov Identifier:
NCT00619437
First received: February 10, 2008
Last updated: NA
Last verified: February 2008
History: No changes posted

February 10, 2008
February 10, 2008
April 2008
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No Changes Posted
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Genetics of Schizophrenia
Genetics of Schizophrenia

Genetic etiology in schizophrenia is widely accepted. However, many chromosomal sites were shown to characterize the families of patients with schizophrenia. This is probably due to the high genetic heterogenity of this illness. Thus, it is important to investigate the genetic factor in relatively genetically homogenous populations. Many studies have indicate that Ashkenazy Jews show relative gentic homogenity. Indeed, the genes responsible for most Mendelian disorders of Jewish peoples have been identified. The study will apply genome-wide mutation screening methods to identify candidate allells in subjects of Ashkenazi Jewish ancestry with multiplex schizophrenia.
Not Provided
Observational
Observational Model: Family-Based
Time Perspective: Prospective
Not Provided
Retention:   Samples With DNA
Description:

Cell Lines / DNA
Non-Probability Sample

schizophrenia
Schizophrenia
Not Provided
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Not Provided

*   Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
 
Not yet recruiting
100
December 2009
Not Provided

Inclusion Criteria:

  1. Age 18+;
  2. Meet DSM-IV criteria for Schizophrenia;
  3. At least one first-degree relative who Meet DSM-IV criteria for Schizophrenia;
  4. Can sign the informed consent form.

Exclusion Criteria:

  1. Patients suffering from terminal or incurabale disease;
  2. Minors, incompetents
Both
18 Years to 78 Years
No
Contact: Raz Gross, MD, MPH 972 3 530 3962 razg@gertner.health.gov.il
Israel
 
NCT00619437
SHEBA-07-4620-RG-CTIL
No
Raz Gross, Head, Mental Health Epidemiology, The Gertner Institute for Epidemiology
Sheba Medical Center
Not Provided
Study Director: Michael Bunzel, MD Psychiatric ward, Sheba Medical Center
Sheba Medical Center
February 2008

ICMJE     Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP