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Interpersonal Psychotherapy for Depressed Adolescents and Parents

This study has been completed.
Sponsor:
Collaborator:
Columbia University
Information provided by (Responsible Party):
New York State Psychiatric Institute
ClinicalTrials.gov Identifier:
NCT00619411
First received: February 11, 2008
Last updated: March 8, 2012
Last verified: March 2012
History of Changes

February 11, 2008
March 8, 2012
November 2007
May 2009   (final data collection date for primary outcome measure)
Clinical Global Improvement (CGI), Hamilton Rating Scale for Depression (HRSD), Center for Epidemiological Studies - Depression Scale (CES-D) [ Time Frame: baseline, week 5, 10, 15 ] [ Designated as safety issue: No ]
CGI, HRSD, CES-D
Complete list of historical versions of study NCT00619411 on ClinicalTrials.gov Archive Site
Global Assessment Scale for Children (C-GAS), Social Adjustment Scale - Self-report (SAS-SR), Conflict Behavior Questionnaire (CBQ-20), Observational assessment of parent-adolescent communication [ Time Frame: baseline, week 5, 10, 15 ] [ Designated as safety issue: No ]
C-GAS, SAS-SR, CBQ-20, Observational assessment of parent-adolescent communication
Not Provided
Not Provided
 
Interpersonal Psychotherapy for Depressed Adolescents and Parents
An Open Clinical Trial of Interpersonal Psychotherapy for Depressed Adolescence and Parents

The purpose of this study is to examine the feasibility and acceptability of an adaptation of Interpersonal Psychotherapy for Depressed Adolescents (IPT-A) that includes greater and more structured involvement of the parents in the treatment.

Adolescent depression is a significant public health problem, and it increases the risk of poor psychosocial outcomes in adolescence and adulthood. Interpersonal Psychotherapy for Depressed Adolescents (IPT-A) has been found to be an effective treatment for reducing adolescents' depressive symptoms and improving their global and social functioning. The purpose of the current study is to examine the feasibility and acceptability of IPT-A when it is delivered with greater and more structured involvement of the parents in the treatment.

Participants will receive 15 weeks of Interpersonal Psychotherapy for Depressed Adolescents and Parents (IPT-AP). Eight the therapy sessions are conducted with the adolescent individually, two are with the parent(s) individually, and five are conducted with the adolescent and parent(s) together. At the end of the 15 weeks, participants who have demonstrated at least a 50% reduction in depressive symptoms will participate in three booster sessions delivered on a monthly basis. All participants will be assessed at baseline, week 5, week 10, week 15 (post-treatment), and 3 months post-treatment to measure depressive symptoms, global and social functioning, and attitudes toward treatment.
Interventional
Phase 1
Allocation: Non-Randomized
Endpoint Classification: Safety/Efficacy Study
Intervention Model: Single Group Assignment
Masking: Open Label
Primary Purpose: Treatment
  • Major Depression
  • Dysthymic Disorder
  • Adjustment Disorders
  • Depressive Disorder Not Otherwise Specified
Behavioral: Interpersonal Therapy for Depressed Adolescents & Parents
15 weekly psychotherapy sessions
Experimental: I
Intervention: Behavioral: Interpersonal Therapy for Depressed Adolescents & Parents
Not Provided

*   Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
 
Completed
10
May 2009
May 2009   (final data collection date for primary outcome measure)

Inclusion Criteria:

  • Meets diagnostic criteria for major depression, dysthymic disorder, depressive disorder not otherwise specified, or adjustment disorder with depressed mood
  • Score between 10 and 28 on the HRSD
  • Score of 65 or less on the C-GAS
  • English-speaking adolescent
  • Parental or legal guardian consent to participate

Exclusion Criteria:

  • Actively suicidal
  • Score greater than 28 on the HRSD
  • Mentally retarded
  • Meets diagnostic criteria for current substance abuse, schizophrenia, bipolar disorder, psychosis, conduct disorder, or eating disorder
  • Currently in active treatment for depression
  • Taking antidepressant medication at the time of baseline assessment
  • Medical illness likely to complicate or interfere with treatment
  • Victim of ongoing or previously undisclosed child abuse
  • Parent psychiatrically hospitalized within the past 3 months
Both
12 Years to 18 Years
No
Contact information is only displayed when the study is recruiting subjects
Not Provided
 
NCT00619411
5549
Yes
New York State Psychiatric Institute
New York State Psychiatric Institute
Columbia University
Principal Investigator: Meredith Gunlicks-Stoessel, Ph.D. University of Minnesota - Clinical and Translational Science Institute
New York State Psychiatric Institute
March 2012

ICMJE     Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP