PolyArginine Treated vEiN grafTs II (PATENT II)

Inclusion Criteria:

1. Subjects must be 25-95 years of age and able to give informed consent.
2. First, isolated coronary artery bypass graft surgery.
3. Use of an apoproved statin and anti-platelet medication for at least 24 months.
4. Agreeable to Cardiovascular imaging at 12 months post-CABG.

Exclusion Criteria:

1. Acute traumatic injury, vasculitis or planned concurrrent ventricular surgical restoration, AICD placement or valvular surgery.
2. Hypercoaguable state.
3. Comorbid illness making 2 year survival unlikely.
4. Participation in another interventional investigative study of a cardiovascular drug or device within 30 days prior to CABG. May participate concurrently in other studies where the intervention/observation will not hinder execution of this study.
5. Patients with any medical condition that, in the investigator's judgment, makes the patient ineligible or places the patient at undue risk (e.g. conditions that preclude standeard invasive follow up procedures such as angiography, i.e. renal failure, bleeding diathesis or peripheral vascular disease preventing catheterization via the groin).
6. Subject has clinical evidence of infection that the Investigator deems significant to the completion of the procedure or that could compromise the subject's safety.
7. Any patient was has undergone more than 20 CAT scans.
8. Any patient who is pregnant.