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Found 119 studies with search of: renin inhibitor
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1 Recruiting Aldosterone Breakthrough During Diovan, Tekturna, and Combination Therapy in Patients With Proteinuric Kidney Disease
Conditions: Proteinuric Kidney Disease;   Diabetic Nephropathy;   Hypertensive Nephrosclerosis;   IGA Nephropathy;   Focal Segmental Glomerulosclerosis;   Glomerulopathy (Obesity-associated)
Interventions: Drug: aliskiren [direct renin inhibitor (DRI)];   Drug: valsartan [angiotensin receptor blocker (ARB)];   Drug: aliskiren + valsartan (DRI + ARB)
2 Completed Phase IIa Safety and Efficacy Study of SPP635 in Mild to Moderate Hypertension
Condition: Hypertension
Intervention: Drug: SPP635 (drug)
3 Recruiting Triple Blockade of the Renin Angiotensin Aldosterone System in Diabetic (Type 1&2) Proteinuric Patients
Conditions: Microalbuminuria;   Macroalbuminuria;   Diabetes;   Proteinuria;   Albuminuria
Intervention: Drug: Aliskiren
4 Not yet recruiting Significance of Regional Ventriculo-arterial Coupling in Patients With Chronic Heart Failure
Condition: Heart Failure
Intervention: Drug: Aliskiren
5 Recruiting Vitamin D Deficiency in Patients With Hypertension
Conditions: Vitamin D Deficiency;   Hypertension
Interventions: Drug: aliskiren (Tekturna);   Dietary Supplement: cholecalciferol (Vitamin D3);   Dietary Supplement: Placebo
6 Not yet recruiting Add-on Aliskiren Treatment in Patients With Chronic Congestive Heart Failure
Condition: Congestive Heart Failure
Interventions: Drug: Aliskiren;   Drug: Placebo
7 Completed Phase IIa Study to Investigate the Efficacy and Safety of SPP635 in Diabetic and Hypertensive Patients With Albuminuria
Conditions: Hypertension;   Type II Diabetes Mellitus
Intervention: Drug: SPP635
8 Recruiting Virtual Hypertension Clinic
Condition: Hypertension
Intervention: Other: Virtual Hypertension Clinic
9 Recruiting Aliskiren and Muscle Sympathetic Nerve Activity
Conditions: Chronic Kidney Disease;   Hypertension;   Muscle Sympathetic Nerve Activity
Intervention: Drug: Aliskiren
10 Recruiting Aliskiren Trial in Type 2 Diabetes Using Cardiovascular and Renal Disease Endpoints
Conditions: Type 2 Diabetes Mellitus;   Cardiovascular Disease
Interventions: Drug: Aliskiren;   Drug: Placebo
11 Active, not recruiting Efficacy and Safety of Aliskiren +/- Ramipril When Added to Amlodipine in Hypertensive Patients With Metabolic Syndrome
Condition: Hypertension With Metabolic Syndrome
Interventions: Drug: ramipril/amlodipine (10/5-10 mg);   Drug: aliskiren/amlodipine (300/5-10 mg);   Drug: aliskiren/ramipril/amlodipine (300/10/5-10mg)
12 Completed Efficacy and Safety of Aliskiren/Amlodipine/Hydrochlorothiazide in Patients With Moderate-Severe Hypertension
Condition: Hypertension
Interventions: Drug: Aliskiren 150/Amlodipine 5 mg, 300/10 mg;   Drug: Aliskiren 150/Hydrochlorothiazide 12.5 mg, 300/25 mg;   Drug: Amlodipine 150/Hydrochlorothiazide 12.5 mg, 10/25 mg;   Drug: Aliskiren 150/Amlodipine 5/Hydrochlorothiazide 12.5 mg, 300/10/25 mg
13 Recruiting Trial to Evaluate the Effect of Tektura (Aliskiren), Angiotensin Inhibitors, Diuretics, and Calcium Channel Blockers on Coronary Flow Reserve in Patients With Type II Diabetes and Hypertension
Conditions: Hypertension;   Diabetes Type 2
Interventions: Drug: Prescribe Aliskiren;   Drug: HCTZ
14 Completed A Clinical Study to Evaluate Renal Hemodynamic Responses to Aliskiren in Patients With Type 2 Diabetes Mellitus
Condition: Type 2 Diabetes Mellitus
Interventions: Drug: aliskiren;   Drug: irbesartan
15 Recruiting Aliskiren for Proteinuric IgAN Despite Angiotensin Blockade
Condition: IGA Nephropathy
Intervention: Drug: Aliskiren
16 Recruiting Efficacy and Safety of Aliskiren and Aliskiren/Enalapril Combination on Morbi-mortality in Patients With Chronic Heart Failure
Condition: Chronic Heart Failure
Interventions: Drug: Enalapril monotherapy;   Drug: Aliskiren monotherapy;   Drug: Aliskiren / Enalapril combination therapy
17 Recruiting Six Months Efficacy and Safety of Aliskiren Therapy on Top of Standard Therapy, on Morbidity and Mortality in Patients With Acute Decompensated Heart Failure
Conditions: Acute Decompensated Heart Failure;   Congestive Heart Failure
Interventions: Drug: Aliskiren;   Drug: Placebo
18 Recruiting Safety and Efficacy of Aliskiren on the Progression of Atherosclerosis in Coronary Artery Disease Patients
Conditions: Coronary Artery Disease (CAD);   Coronary Atherosclerosis
Interventions: Drug: Placebo;   Drug: Aliskiren
19 Recruiting Safety and Efficacy Study of Add On Aliskiren in Patients With Heart Failure and Renal Impairment
Conditions: Heart Failure;   Kidney Failure
Interventions: Drug: Aliskiren;   Drug: Placebo
20 Not yet recruiting Safety of Add on Aliskiren to Angiotensin Converting Enzyme Inhibitor (ACEI) and Angiotensin I Receptor Blocker (ARB) Treatment in Type 2 Diabetes With Nephropathy
Condition: Type 2 Diabetes With Nephropathy
Intervention: Drug: Aliskiren 300mg/d

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