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Found 128 studies with search of: alteplase
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Rank Status Study
1 Terminated Alteplase for Blood Flow Restoration in Hemodialysis Catheters
Condition: Thrombosis
Interventions: Drug: Alteplase "push" protocol;   Drug: alteplase dwell arm
2 Completed Low Dosage of rt-PA in the Treatment of Pulmonary Thromboembolism in China
Conditions: Pulmonary Embolism;   Thromboembolism
Intervention: Drug: rt-PA
3 Recruiting Interventional Management of Stroke (IMS) III Trial
Condition: Acute Ischemic Stroke
Interventions: Drug: IV rt-PA;   Drug: IA rt-PA (Investigational);   Device: Standard Microcatheter Infusion (all commercially available models);   Device: EKOS Micro-Infusion (NeuroWave Infusion) System;   Device: Concentric Merci® Retriever (all FDA approved commercially available models);   Device: The Penumbra System™ (all FDA approved commercially available models)
4 Terminated Safety and Efficacy of Tissue Plasminogen Activator (tPA) in Neonates and Infants
Condition: Catheterization
Intervention: Drug: alteplase
5 Completed Post-Marketing Clinical Study of Alteplase for Acute Ischemic Stroke （Japan Alteplase Clinical Trial Ⅱ：J-ACT Ⅱ）
Condition: Stroke
Intervention: Drug: Alteplase
6 Not yet recruiting Study for the Use of Alteplase in Patients Who Awaken With Stroke
Condition: Ischemic Stroke
Intervention: Drug: Alteplase (tPA)
7 Completed Japan Alteplase Clinical Trial(J-ACT): Efficacy and Safety Study of Tissue Plasminogen Activator for Ischemic Stroke
Conditions: Cerebral Infarction;   Brain Ischemia
Intervention: Drug: alteplase
8 Active, not recruiting IV vs. IA tPA (Activase) in Acute Ischemic Stroke With CTA Evidence of Major Vessel Occlusion
Condition: Ischemic Stroke
Intervention: Drug: IV tpa (Alteplase) vs IA tpa (Alteplase)
9 Completed Trial to Compare the Efficacy and Safety of a Single Bolus of TNK-tPA (Tenecteplase, Metalyse®) With Accelerated Infusion of rt-PA (Alteplase, Actilyse®) in Asian Patients With Acute Myocardial Infarction
Condition: Myocardial Infarction
Interventions: Drug: TNK-tPA;   Drug: rt-PA
10 Recruiting Study of the Combination Therapy of Rt-PA and Eptifibatide to Treat Acute Ischemic Stroke
Conditions: Acute Ischemic Stroke;   Stroke;   Brain Infarction
Interventions: Drug: Eptifibatide;   Drug: rt-PA
11 Active, not recruiting Low-Dose Alteplase to Treat Blood Clots in Deep Leg Veins
Condition: Venous Thrombosis
Intervention: Drug: Alteplase (Activase, Genentech)
12 Completed A Study to Evaluate the Effects of YM872 on Brain Function and Disability When Administered in Combination With Alteplase (Tissue Plasminogen Activator)
Condition: Acute Ischemic Stroke
Intervention: Drug: YM872 (zonampanel), t-PA (alteplase)
13 Completed Cathflo Activase Pediatric Study
Condition: Dysfunctional Central Venous Access Devices (CVADS)
Intervention: Drug: Cathflo Activase (Alteplase)
14 Recruiting Acute Venous Thrombosis: Thrombus Removal With Adjunctive Catheter-Directed Thrombolysis
Conditions: Deep Vein Thrombosis;   Venous Thrombosis;   Postphlebitic Syndrome;   Venous Thromboembolism;   Post Thrombotic Syndrome
Intervention: Drug: Recombinant tissue plasminogen activator (rt-PA)
15 Completed Low-Dose rtPA to Treat Blood Clots in Major Arm or Neck Veins
Condition: Thrombosis
Intervention: Procedure: Pulse-sprayed injection of recombinant tissue plasminogen activator (rtPA)
16 Recruiting Alteplase for Treatment of Empyema and Complicated Parapneumonic Effusion
Conditions: Empyema;   Pleural Effusion
Intervention: Drug: Alteplase
17 Completed Combined Treatment With Alteplase (rt-PA) and Cerebrolysin® in Acute Ischemic Hemispheric Stroke
Condition: Stroke
Interventions: Drug: Cerebrolysin;   Drug: 0.9% Saline Solution
18 Suspended FRALYSE Trial: Comparison of the Classical rt-PA Procedure With a Longer Procedure in Acute Ischemic Stroke
Condition: Stroke, Acute
Interventions: Drug: alteplase 0.9mg/kg over 60 minutes;   Drug: alteplase 0.8mg/kg over 90 minutes
19 Completed Combined Approach to Lysis Utilizing Eptifibatide and rt-PA in Acute Ischemic Stroke (CLEAR Stroke) Trial
Condition: Stroke
Interventions: Drug: activase;   Drug: integrilin
20 Recruiting Intraventricular Rt-PA in Patients With Intraventricular Hemorrhage
Condition: Cerebral Hemorrhage
Intervention: Drug: Recombinant Tissue Plasminogen Activator (rt-PA)

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